In biomedical research, high-throughput screening is often applied as it comes with automatization, higher-efficiency, and more and faster results.High-throughput screening experiments encompass drug, drug combination, genetic perturbagen or a combination of genetic and chemical perturbagen screens.These experiments are conducted in real-time assay
A Model Curriculum for an Emergency Medical Services (EMS) Rotation for Emergency Medicine Residents
Audience: This EMS curriculum is designed for Emergency Medicine residents at all levels of training.Introduction: Emergency Medicine (EM) physicians have routine interaction with Emergency Medical Services (EMS) in their clinical practice.Additionally, the American College of Graduate Medical Education (ACGME) mandates that all Emergency Medicine
Cocktail of chemical compounds robustly promoting cell reprogramming protects liver against acute injury
Abstract Tissue damage induces cells into reprogramming-like cellular Womens Pants state, which contributes to tissue regeneration.However, whether factors promoting the cell reprogramming favor tissue regeneration remains elusive.Here we identified combination of small chemical compounds including drug cocktails robustly promoting in vitro cell re
SLAM Family Receptor Signaling in Viral Infections: HIV and Beyond
The signaling lymphocytic activation molecule (SLAM) family of receptors are expressed on the majority of immune cells.These receptors often serve as self-ligands, and play important roles in cellular communication and adhesion, thus modulating immune responses.SLAM family receptor signaling is differentially regulated in various immune cell types,